TAKE AWAYS
What You Can't Miss – In a Nutshell
Stabilizing glucose has a great impact on diagnoses rates of diabetes
- Glucose declines rapidly in whole blood - at a rate of 7-8% per hour - so preventing this decline is important for accurate diagnosis of diabetes mellitus
Some stabilization methods are imperfect or impractical
- Sodium fluoride is a commonly used stabilizer, but whilst it inhibits enolase in the glycolytic pathway, other enzymes remain active and continue to metabolize glucose
Using a VACUETTE® FC Mix tube does the job
- FC Mix tubes contain fluoride to inhibit enolase, citric acid to acidify the sample and inhibit other glycolytic enzymes, as well as EDTA that chelates the magnesium.