Sustainability in Preanalytics

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EPISODE 3 - SEASON 1

Dr. Mads Nybo presents:

  • Release Date: 01.04.2025
  • Duration: 33 minutes
  • Guest: Dr. Mads Nybo
  • Host: Director Global Medical & Clinical Affairs Ana-Maria Å imundić
  • Introduction: Dr. Mads Nybo, chief physician at the Clinical Biochemistry department of the Odense University Hospital shares his views on and experience with sustainability in the medical sector.
A Detailed Breakdown of Key Moments

Timestamps for Episode 3

  • 01:33 - Sustainability is very much the word on the agenda 
  • 02:50 - Looking at Preanalytics from a sustainable point of view
  • 04:53- The situation in Denmark
  • 06:20- Finding a systematic approach
  • 08:08- Laboratory solutions already in practice
  • 10:45 - The demand management concept and low volume tubes
  • 19:30 - Waste in laboratories
  • 21:49 - Could blood collection tubes be circular?
Take Aways

What You Can't Miss – In a Nutshell

Stabilizing glucose has a great impact on diagnoses rates of diabetes

  • Glucose declines rapidly in whole blood - at a rate of 7-8% per hour - so preventing this decline is important for accurate diagnosis of diabetes mellitus

Some stabilization methods are imperfect or impractical

  • Sodium fluoride is a commonly used stabilizer, but whilst it inhibits enolase in the glycolytic pathway, other enzymes remain active and continue to metabolize glucose

Using a VACUETTEĀ® FC Mix tube does the job

  • FC Mix tubes contain fluoride to inhibit enolase, citric acid to acidify the sample and inhibit other glycolytic enzymes, as well as EDTA that chelates the magnesium.

ā€œAnd so stabilizing glucose to prevent its decline, has a great impact on those, the incidence of diabetes, diagnoses rates, so stabilizing glucose, to prevent its decline is quite important.ā€

Dr. David Grenache

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Mads Nybo mentioned this clinical trial conducted in 25 adult medical-surgical ICUs in Canada. The findings encouraged the Odense Hospital Team to reduce blood collection tube volumes.

jamanetwork.com/journals/jama/fullarticle/2810758

Chapter 7.2.4.1 - General instructions on primary sample collection and handling include reviewing the sample volume requirements periodically to ensure that neither excessive nor insufficient amounts are collected.

www.iso.org/standard/76677.html

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